Table 11
Birth Defect Numbers & Prevalence Rates by Detailed Diagnostic Code Group and
Age of Mother
Michigan Resident Children Born in Michigan During 2012 - 2017,
Cases Diagnosed within One Year from Birth
Six-year Birth Defect Totals & Birth Defect Prevalence Rates

Birth Defects

  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
A Central Nervous System (All) 3,576 293 852 1,005 904 519 53.2 71.7 55.4 48.7 50.7 56.5
  A01 Anencephalus 64 6 16 20 13 9 1.0 1.5 1.0 1.0 0.7 1.0
  A02 Spina Bifida w/o Anencephaly 273 21 69 73 60 50 4.1 5.1 4.5 3.5 3.4 5.4
  A03 Hydrocephalus w/o Spina Bifida 508 40 141 136 125 64 7.6 9.8 9.2 6.6 7.0 7.0
  A04 Encephalocele 79 4 20 19 23 13 1.2 * 1.3 0.9 1.3 1.4
  A05 Microcephalus 1,002 89 275 293 227 117 14.9 21.8 17.9 14.2 12.7 12.7
  A06 Holoprosencephaly --- --- --- --- --- --- --- --- --- --- --- ---
  A99 Other CNS Anomalies 2,197 163 482 611 600 340 32.7 39.9 31.3 29.6 33.6 37.0
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
B Eye (All) 2,504 150 498 701 715 440 37.3 36.7 32.4 34.0 40.1 47.9
  B01 Anopthalmos
/Micropthalmos
97 9 20 25 27 16 1.4 2.2 1.3 1.2 1.5 1.7
  B02 Congenital Cataract 130 9 28 32 39 22 1.9 2.2 1.8 1.6 2.2 2.4
  B03 Aniridia 20 1 7 1 5 6 0.3 * 0.5 * * 0.7
  B99 Other Eye Anomalies 2,361 141 469 664 677 410 35.1 34.5 30.5 32.2 38.0 44.7
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
C Ear, Face and Neck (All) 2,161 113 483 650 559 356 32.2 27.6 31.4 31.5 31.3 38.8
  C01 Anotia/Microtia 124 4 29 39 31 21 1.8 * 1.9 1.9 1.7 2.3
  C99 Other Ear, Face &
Neck Anomalies
2,133 111 476 639 555 352 31.8 27.1 30.9 31.0 31.1 38.3

Table 11
Birth Defect Numbers & Prevalence Rates by Detailed Diagnostic Code Group and
Age of Mother
Michigan Resident Children Born in Michigan During 2012 - 2017,
Cases Diagnosed within One Year from Birth
Six-year Birth Defect Totals & Birth Defect Prevalence Rates
(Continued)

Birth Defects

  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
D Heart & Circulatory System (All) 14,602 967 3,313 4,230 3,679 2,412 217.4 236.5 215.3 205.1 206.3 262.7
  D01 Common Truncus 85 9 16 21 27 12 1.3 2.2 1.0 1.0 1.5 1.3
  D02 Transposition of Great
Vessels
348 21 71 96 106 54 5.2 5.1 4.6 4.7 5.9 5.9
  D03 Tetralogy of Fallot 358 25 78 103 98 54 5.3 6.1 5.1 5.0 5.5 5.9
  D04 Ventricular Septal Defect 3,344 211 731 933 858 611 49.8 51.6 47.5 45.2 48.1 66.6
  D05 Atrial Septal Defect 9,046 608 2,119 2,617 2,217 1,484 134.7 148.7 137.7 126.9 124.3 161.6
  D06 Atrioventricular Septal Defect (Endocardial Cushion Defect) 215 16 37 51 61 50 3.2 3.9 2.4 2.5 3.4 5.4
  D07 Pulmonary Valve
Atresi& Stenosis
706 58 166 191 183 108 10.5 14.2 10.8 9.3 10.3 11.8
  D08 Tricuspid Valve
Atresi& Stenosis
78 11 16 23 14 14 1.2 2.7 1.0 1.1 0.8 1.5
  D09 Ebstein's Anomaly 51 4 18 12 10 7 0.8 * 1.2 0.6 0.6 0.8
  D10 Aortic Valve Stenosis 162 10 29 48 47 28 2.4 2.4 1.9 2.3 2.6 3.0
  D11 Hypoplastic Left Heart
Syndrome
283 21 86 80 65 31 4.2 5.1 5.6 3.9 3.6 3.4
  D12 Patent Ductus Arteriosis 4,941 354 1,111 1,439 1,196 840 73.6 86.6 72.2 69.8 67.1 91.5
  D13 Coarctation of Aorta 549 28 137 164 139 81 8.2 6.8 8.9 8.0 7.8 8.8
  D14 Pulmonary Artery Anomalies 685 42 169 186 174 114 10.2 10.3 11.0 9.0 9.8 12.4
  D15 Interrupted Aortic Arch 33 3 5 9 13 3 0.5 * * 0.4 0.7 *
  D16 Total Anomalous Pulmonary
Venous Return (or connection)
54 6 16 16 12 4 0.8 1.5 1.0 0.8 0.7 *
  D17 Double Outlet Right Ventricle 102 14 23 22 30 13 1.5 3.4 1.5 1.1 1.7 1.4
  D18 Common Ventricel 75 8 17 21 17 12 1.1 2.0 1.1 1.0 1.0 1.3
  D99 Other Heart &
Circulatory System
Anomalies
5,043 303 1,047 1,491 1,341 860 75.1 74.1 68.0 72.3 75.2 93.7
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
E Respiratory System (All) 3,765 233 957 1,069 952 552 56.1 57.0 62.2 51.8 53.4 60.1
  E01 Lung Agenesis/
Hypoplasia
261 20 54 84 67 36 3.9 4.9 3.5 4.1 3.8 3.9
  E02 Choanal Atresia 133 9 33 34 35 22 2.0 2.2 2.1 1.6 2.0 2.4
  E99 Other Respiratory
System Anomalies
3,506 214 901 983 889 517 52.2 52.3 58.5 47.7 49.8 56.3
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
F Cleft Palate & Cleft Lip 1,127 53 266 346 297 165 16.8 13.0 17.3 16.8 16.7 18.0
  F01 Cleft Palate 415 18 93 127 113 64 6.2 4.4 6.0 6.2 6.3 7.0
  F02 Cleft Lip w & w/o Cleft Palate 712 35 173 219 184 101 10.6 8.6 11.2 10.6 10.3 11.0

Table 11
Birth Defect Numbers & Prevalence Rates by Detailed Diagnostic Code Group and
Age of Mother
Michigan Resident Children Born in Michigan During 2012 - 2017,
Cases Diagnosed within One Year from Birth
Six-year Birth Defect Totals & Birth Defect Prevalence Rates
(Continued)

Birth Defects

  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
G Upper Alimentary Caanal/
Digestive System (All)
3,286 244 894 956 737 455 48.9 59.7 58.1 46.4 41.3 49.6
  G01 Esophageal Atresia/
Tracheoesophageal Fistula
152 11 33 37 41 30 2.3 2.7 2.1 1.8 2.3 3.3
  G02 Rectal & Large Intestinal
Atresia/Stenosis
302 14 81 91 71 45 4.5 3.4 5.3 4.4 4.0 4.9
  G03 Pyloric Stenosis 1,070 97 341 308 207 117 15.9 23.7 22.2 14.9 11.6 12.7
  G04 Hirshsprung's Disease
(congenital megacolon)
299 15 74 99 62 49 4.5 3.7 4.8 4.8 3.5 5.3
  G05 Biliary Atresia 84 7 28 18 19 12 1.3 1.7 1.8 0.9 1.1 1.3
  G99 Other Upper
Alimentary Canal
/Digestive System Anomalies
1,727 118 432 503 420 254 25.7 28.9 28.1 24.4 23.5 27.7
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
H Genital & Urinary Systems 10,981 689 2,465 3,259 2,882 1,684 163.5 168.5 160.2 158.0 161.6 183.4
  H01 Renal Agenesis/
Hypoplasia
432 27 103 132 100 70 6.4 6.6 6.7 6.4 5.6 7.6
  H02 Bladder Exstrophy &
Cloacal Exstrophy
17 - 4 6 6 1 0.3 - * 0.3 0.3 *
  H03 Obstructive Genitourinary
Defects
2,418 133 491 723 665 405 36.0 32.5 31.9 35.1 37.3 44.1
  H04 Hypospadias 2,453 140 527 732 686 368 36.5 34.2 34.2 35.5 38.5 40.1
  H05 Epispadias 39 2 11 12 8 6 0.6 * 0.7 0.6 0.4 0.7
  H99 Other Genital
& Urinary System
Anomalies
7,277 471 1,670 2,145 1,889 1,101 108.3 115.2 108.5 104.0 105.9 119.9

Table 11
Birth Defect Numbers & Prevalence Rates by Detailed Diagnostic Code Group and
Age of Mother
Michigan Resident Children Born in Michigan During 2012 - 2017,
Cases Diagnosed within One Year from Birth
Six-year Birth Defect Totals & Birth Defect Prevalence Rates
(Continued)

Birth Defects

  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
I Musculoskeletal System (All) 14,653 882 3,270 4,288 3,979 2,231 218.1 215.7 212.5 207.9 223.1 243.0
  I01 Upper Limb Reduction
Deformities
162 10 47 38 47 20 2.4 2.4 3.1 1.8 2.6 2.2
  I02 Lower Limb Reduction
Deformities
147 13 36 44 29 25 2.2 3.2 2.3 2.1 1.6 2.7
  I03a Exomphalos/
Omphalocele
157 10 43 46 39 19 2.3 2.4 2.8 2.2 2.2 2.1
  I03b Gastroschisis 273 65 108 68 26 6 4.1 15.9 7.0 3.3 1.5 0.7
  I03c Prune Belly Syndrome,
Congenital Hernia of Bladder
175 24 48 45 36 21 2.6 5.9 3.1 2.2 2.0 2.3
  I04 Congenital Hip Dislocation 582 27 120 171 176 88 8.7 6.6 7.8 8.3 9.9 9.6
  I05 Diaphragmatic Hernia 203 19 42 54 53 35 3.0 4.6 2.7 2.6 3.0 3.8
  I99 Other Musculoskeletal
System
13,642 759 2,995 4,018 3,748 2,120 203.1 185.6 194.6 194.8 210.1 230.9
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
J Integument (All) 8,467 799 2,621 2,325 1,747 975 126.1 195.4 170.3 112.7 97.9 106.2
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
K Chromosomal Anomalies 1,811 96 311 419 414 570 27.0 23.5 20.2 20.3 23.2 62.1
  K01 Trisomy 13 49 8 6 12 10 13 0.7 2.0 0.4 0.6 0.6 1.4
  K02 Down Syndrome 865 33 111 148 200 372 12.9 8.1 7.2 7.2 11.2 40.5
  K03 Trisomy 18 92 1 11 12 19 49 1.4 * 0.7 0.6 1.1 5.3
  K04 Chromosome 22q11.2
Deletion Syndrome
20 2 4 7 2 5 0.3 * * 0.3 * *
  K05 Turner Syndrome 6 - 4 2 - - 0.1 - * * - -
  K99 Other Chromosomal
Anomalies
869 57 194 254 203 161 12.9 13.9 12.6 12.3 11.4 17.5
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
L Other and Unspecified
Birth Defects
14,390 655 2,763 4,172 4,240 2,556 214.2 160.2 179.5 202.3 237.7 278.4

Table 11
Birth Defect Numbers & Prevalence Rates by Detailed Diagnostic Code Group and
Age of Mother
Michigan Resident Children Born in Michigan During 2012 - 2017,
Cases Diagnosed within One Year from Birth
Six-year Birth Defect Totals & Birth Defect Prevalence Rates
(Continued)

Other Reportable Conditions

  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
M Infectious Conditions
Occurring in the Perinatal
Period
404 65 121 95 71 52 6.0 15.9 7.9 4.6 4.0 5.7
  M01 Syphilis 102 6 25 22 23 26 1.5 1.5 1.6 1.1 1.3 2.8
  M02 Other Infections 304 59 96 73 48 28 4.5 14.4 6.2 3.5 2.7 3.0
  M03 Zika Virus Disease - - - - - - - - - - - -
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
N Familial/Congenital
Neoplasms
90 6 17 29 22 16 1.3 1.5 1.1 1.4 1.2 1.7
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
O Endocrine/Metabolic
Disorders
5,112 354 1,230 1,498 1,281 749 76.1 86.6 79.9 72.6 71.8 81.6
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
P Diseases of the Blood
& Blood Forming Organs
2,699 259 880 737 522 299 40.2 63.3 57.2 35.7 29.3 32.6
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
Q Other Diseases of the
Central and Peripheral
Nervous System
2,705 195 637 749 691 432 40.3 47.7 41.4 36.3 38.7 47.1
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
R Other Diseases of the Eye 3,891 248 907 1,131 971 634 57.9 60.7 58.9 54.8 54.4 69.1
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
S Hearing Deficiency 6,307 385 1,373 1,853 1,657 1,036 93.9 94.2 89.2 89.8 92.9 112.8
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
T Other Diseases of the
Heart & Circulatory System
3,202 235 833 910 795 429 47.7 57.5 54.1 44.1 44.6 46.7

Table 11
Birth Defect Numbers & Prevalence Rates by Detailed Diagnostic Code Group and
Age of Mother
Michigan Resident Children Born in Michigan During 2012 - 2017,
Cases Diagnosed within One Year from Birth
Six-year Birth Defect Totals & Birth Defect Prevalence Rates
(Continued)

Other Reportable Conditions

  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
U Other Diseases of the
Gastrointestinal System
3,637 228 876 1,078 905 547 54.1 55.8 56.9 52.3 50.7 59.6
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
V Other Diseases of the
Genital and Urinary Systems
966 54 179 279 284 170 14.4 13.2 11.6 13.5 15.9 18.5
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
X Other Musculoskeletal
System Diseases
16 1 4 6 5 - 0.2 * * 0.3 * -
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
Y Maternal Exposures
Affecting Fetus
4,729 238 1,261 1,602 1,080 547 70.4 58.2 81.9 77.7 60.5 59.6
  Y01 Newborn Affected by
Maternal use of Alcohol
73 1 11 15 24 22 1.1 * 0.7 0.7 1.3 2.4
  Y02 Fetal Alcohol Syndrome --- --- --- --- --- --- --- --- --- --- --- ---
  Y99 Other Maternal Exposures
Affecting the Fetus
4,682 237 1,254 1,590 1,064 536 69.7 58.0 81.5 77.1 59.7 58.4
  Diagnostic Grouping Number by Race Prevalence Rate by Race
Total 15‑19 20‑24 25‑29 30‑34 35 & Over Total 15‑19 20‑24 25‑29 30‑34 35 & Over
One or More
Reportable Diagnosis 
79,519 5,090 18,670 23,410 20,479 11,853 1,183.8 1,244.9 1,213.2 1,135.0 1,148.1 1,291.1

Notes:

Mothers' Age: Counts of birth defects for mothers ages 15-19 years old include mothers who were less than 15; Prevalence rates are for mothers less than 19 per 10,000 mothers ages 15-19.

Rates Are Per 10,000 Michigan Born Resident Live Births.  Rates include all children reported with a birth defect who were born in Michigan and whose mother was a resident at the time of birth. This enables the calculation of birth defects prevalence rates. Birth defect statistics sometimes reflect trends related to data reporting or new testing. See Data Quality Considerations for further details.
Symbols: *: Figure does not meet standards of reliability or precision. •  -: A dash represents quantity zero. •  0.0: Quanity more than zero but less than 0.05.
Conditions are reportable if identified within the first two years of a child's life. The prevalence frequencies used to calculate the rates in this table represent cases diagnosed within the first year of life.
Prior to October 2015, diagnoses were coded using the 9th revision to the International Classification of Diseases - ICD–9–CM.  (See Birth Defect Groups and ICD–9–CM Diagnosis Codes for the codes used to categorize birth defects.) After October 2015, the Birth Defect registry coded diagnoses using ICD–10–CM. (See Birth Defect Groups and ICD–10–CM Diagnosis Codes for the codes used to categorize birth defects.) Diagnostic Code Groupings used in analysis of birth defects are defined by the Centers for Disease Control.
Source: Michigan Birth Defects Registry, Division for Vital Records & Health Statistics, Michigan Department of Health & Human Services
Reports Processed through May 28, 2020

Last Updated on August 17, 2020