Number of Deaths and Age-adjusted Mortality Rates for the Ten Leading Causes of Death,
Hillsdale County,
Michigan and United States Residents, 2021

Michigan Rank & Cause of Death Number of Deaths Age-adjusted Mortality Rates
Hillsdale MI U.S. Hillsdale MI U.S.
All Causes of Death653   117,756   3,464,231   1,048.5 942.4 879.7
1. Heart Disease132   26,651   695,547   204.5 209.3 173.8
2. Cancer115   21,221   605,213   169.3 160.2 146.6
3. COVID-19108   13,614   416,893   165.8 106.9 104.1
4. Unintentional Injuries32   6,568   224,935   74.6 61.8 64.7
5. Stroke24   5,771   162,890   39.3 46.1 41.1
6. Chronic Lower Respiratory Diseases44   5,217   142,342   62.2 39.5 34.7
7. Alzheimer's Disease20   4,197   119,399   32.4 34.3 31.0
8. Diabetes Mellitus16   3,440   103,294   * 26.7 25.4
9. Kidney Disease9   1,963   54,358   * 15.5 13.6
10. Chronic Liver Disease and Cirrhosis10   1,799   56,585   * 15.1 14.5
       

Note: Rates are per 100,000 population. The causes of death are listed in order of the 10 leading causes of death for Michigan residents in 2021.

Death records with gender not stated are included only in the "Total" column.

*:  An asterisk (*) indicates that the data do not meet standards of reliability or precision.

Data displayed are by the underlying cause of death which is the condition giving rise to the chain of events leading to death. Causes of death are classified in accordance with the Tenth Revision of the International Classifications of Diseases (ICD-10), a coding structure developed by the World Health Organization. This revision has been used to classify deaths occurring on or after January 1, 1999. The ICD-10 codes are grouped into broader categories for the causes listed in this table in order to classify these selected causes of death (e.g., ICD-10 codes C00-C97 are used to indicate deaths due to cancer).

Source: 2021 Geocoded Michigan Death Certificate Registry.     Division for Vital Records & Health Statistics, Michigan Department of Health & Human Services; Population Estimates by Age and Race (latest update 7/2025), U.S Census Bureau. .

Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2021 on CDC WONDER Online Database, released 2023.

Last Updated: 02/03/2025