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Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2008,
Cases Diagnosed within One Year from Birth

Congenital Anomalies (740 - 759)

Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
A Congenital Anomalies of the
Central Nervous System 		39.1 35.7 38.8 40.3 38.1 39.9 42.0 41.5 42.6 37.8 35.2
  A01 Anencephalus 1.2 1.6 0.5 1.2 1.4 1.1 1.6 1.0 1.1 0.6 1.5
  A02 Spina Bifida w/o Anencephaly 4.6 3.6 5.5 3.4 4.0 4.9 4.9 4.9 5.1 4.6 5.2
  A03 Hydrocephalus w/o Spina Bifida 9.8 10.1 11.5 10.4 9.0 9.5 10.3 9.6 9.2 10.0 8.4
  A04 Encephalocele 1.1 1.2 0.8 1.0 1.1 1.1 1.0 1.7 1.0 0.9 0.8
  A05 Microcephalus 9.4 8.9 8.9 10.8 9.1 9.4 9.7 10.1 10.7 10.0 6.3
  A99. All Other CNS
Anomalies 		20.5 16.3 19.0 20.5 21.3 21.6 22.7 23.0 23.2 19.5 19.4
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
B Congenital Anomalies of the Eye 26.8 27.9 28.4 29.9 29.0 25.1 27.8 27.8 22.9 24.2 22.4
  B01 Anopthalmos/Micropthalmos 1.9 1.6 2.4 2.7 2.2 1.7 1.9 2.0 1.6 1.7 1.3
  B02 Congenital Cataract 2.4 2.9 2.5 2.8 2.7 2.2 2.3 2.9 1.6 1.9 2.0
  B03 Aniridia 0.3 * * * * 0.3 0.5 * * * *
  B99. All Other Congenital
Anomalies of the Eye 		24.3 25.7 25.8 26.7 26.2 22.7 25.2 25.0 21.4 21.7 20.0
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
C Congenital Anomalies of the
Ear, Face and Neck 		16.0 15.9 16.8 17.6 16.2 15.5 15.1 19.7 14.0 13.1 15.5
  C01 Anotia/Microtia 1.3 1.6 1.4 1.5 1.7 1.1 1.4 1.0 1.0 1.1 1.1
  C99. All Other Congenital
Anomalies of the Ear, Face and Neck 		15.6 15.4 16.6 16.9 16.1 15.1 14.6 19.5 13.9 12.5 14.9

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2008,
Cases Diagnosed within One Year from Birth
(Continued)

Congenital Anomalies (740 - 759)
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
D Congenital Anomalies of the
Heart and Circulatory System 		177.2 147.2 159.4 172.4 174.9 189.0 188.2 189.6 198.9 180.0 188.1
  D01 Common Truncus 1.3 0.8 1.6 1.0 1.9 1.3 1.2 1.3 1.3 1.2 1.7
  D02 Transposition of Great
Vessels 		5.0 5.0 4.2 5.2 4.3 5.3 4.6 6.7 5.3 5.1 4.8
  D03 Tetralogy of Fallot 5.4 5.5 5.2 5.3 6.2 5.2 4.3 5.3 5.5 4.7 6.4
  D04 Ventricular Septal Defect 41.2 38.0 37.7 41.0 40.9 42.7 41.0 44.8 43.3 40.5 43.9
  D05 Atrial Septal Defect 78.2 56.5 60.5 69.9 73.9 89.2 83.2 91.8 97.0 80.8 93.5
  D06 Endocardial Cushion Defect 5.6 4.8 5.6 5.8 6.7 5.5 5.7 5.5 5.9 5.1 5.1
  D07 Pulmonary Valve
Atresia and Stenosis 		11.5 10.2 12.2 10.0 12.8 11.7 9.9 13.7 12.9 11.5 10.3
  D08 Tricuspid Valve
Atresia and Stenosis 		1.5 1.3 2.1 2.0 1.7 1.3 0.8 1.7 0.9 1.5 1.3
  D09 Ebstein's Anomaly 1.6 2.6 3.4 2.9 1.4 0.7 0.8 1.0 0.6 * 0.9
  D10 Aortic Valve Stenosis 2.5 3.1 2.1 2.4 2.6 2.5 2.8 2.7 2.2 2.5 2.2
  D11 Hypoplastic Left Heart
Syndrome 		4.0 3.4 4.9 4.3 4.2 3.9 3.9 4.7 3.4 3.9 3.5
  D12 Patent Ductus Arteriosis 51.7 37.3 43.3 46.4 54.6 57.1 54.6 57.9 61.6 52.0 59.7
  D13 Coarctation of Aorta 6.2 6.0 5.2 6.6 6.6 6.3 5.9 5.9 6.5 6.1 7.0
  D14 Pulmonary Artery Anomalies 20.1 17.9 20.7 21.2 20.2 20.3 18.4 22.3 22.5 18.9 19.2
  D99. All Other Congenital
Anomalies of the
Heart and Circulatory System 		76.0 63.4 67.1 77.0 76.9 80.3 88.9 74.1 86.1 77.7 74.2
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
E Congenital Anomalies of the
Respiratory System 		53.2 39.1 44.1 46.2 57.0 58.8 51.4 57.3 79.4 68.6 36.4
  E01 Lung Agenesis/Hypoplasia 6.9 6.1 5.5 6.6 11.7 6.4 8.4 7.4 5.4 4.5 6.0
  E02 Choanal Atresia 1.6 1.4 2.0 2.3 1.4 1.5 1.5 1.8 1.4 1.2 1.4
  E99. All Other Congenital
Anomalies of the Respiratory
System 		47.4 33.6 39.0 40.8 46.8 53.6 44.1 51.4 75.3 64.7 31.6
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
F Cleft Palate and Cleft Lip 15.8 14.8 17.0 15.9 16.9 15.5 14.7 15.6 17.1 15.9 14.3
  F01 Cleft Palate 5.7 5.3 6.3 5.6 5.5 5.7 4.8 5.6 6.4 6.1 5.7
  F02 Cleft Lip w and w/o Cleft Palate 10.1 9.5 10.7 10.3 11.4 9.8 9.8 10.0 10.7 9.7 8.6

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2008,
Cases Diagnosed within One Year from Birth
(Continued)

Congenital Anomalies (740 - 759)
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
G Congenital Anomalies of the Upper
Alimentary Canal/ Digestive System 		52.7 53.8 58.4 56.5 48.8 51.3 50.8 50.5 59.8 51.8 43.3
  G01 Esophageal Atresia/
Tracheoesophageal Fistula 		3.0 2.5 3.5 3.3 3.5 2.9 3.4 3.3 2.5 2.9 2.1
  G02 Rectal and Large Intestinal
Atresia/Stenosis 		4.8 5.3 4.6 5.0 4.6 4.7 4.8 4.8 5.6 4.2 4.4
  G03 Pyloric Stenosis 16.4 16.3 20.9 18.0 14.7 15.4 14.4 13.9 16.7 14.9 17.4
  G04 Hirshsprung's Disease
(congenital megacolon) 		2.9 2.7 3.3 3.3 2.9 2.7 3.2 2.7 2.7 2.7 2.3
  G05 Biliary Atresia 1.1 1.2 1.1 0.8 1.2 1.1 1.4 1.0 1.0 0.9 1.2
  G99. Other Cong. Anomalies
of Upper Alimentary Canal
/ Digestive System 		28.2 29.7 28.4 30.1 26.3 27.9 27.9 28.5 34.6 29.2 18.6
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
H Congenital Anomalies of the
Genital and Urinary Systems 		137.2 145.3 135.5 137.5 133.0 136.5 134.3 143.9 150.0 136.5 117.0
  H01 Renal Agenesis/Hypoplasia 5.7 7.1 5.2 6.4 5.9 5.4 4.8 5.3 4.3 6.1 6.4
  H02 Bladder Exstrophy 0.3 * 0.8 0.5 * 0.2 * 0.5 * * *
  H03 Obstructive Genitourinary
Defects 		21.8 19.1 20.9 22.1 22.2 22.5 22.6 24.9 22.9 21.3 20.9
  H04 Hypospadias &
Epispadias 		30.6 32.9 29.1 30.7 29.7 30.6 28.1 35.7 26.1 28.5 34.5
  H99. All Other Congenital
Anomalies of the Genital
& Urinary Systems 		114.0 120.3 113.7 113.9 111.1 113.4 114.5 118.2 130.1 115.8 86.9
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
I Congenital Anomalies of the
Musculoskeletal System 		165.3 153.5 168.2 176.6 162.5 165.5 150.6 175.2 190.3 180.1 130.2
  I01 Upper Limb Reduction Deformities 2.5 3.1 2.4 2.9 2.8 2.3 1.9 2.0 2.1 2.6 3.0
  I02 Lower Limb Reduction Deformities 1.9 1.6 2.0 2.0 1.9 2.0 2.1 2.3 2.1 1.7 1.5
  I03 Gastroschisis/Omphalocele 5.1 4.2 5.2 3.7 4.6 5.6 4.8 5.3 6.5 6.4 5.1
  I04 Congenital Hip Dislocation 12.6 14.6 16.2 15.9 13.1 10.6 11.3 9.3 12.9 8.0 11.2
  I05 Diaphragmatic Hernia 3.2 2.9 3.2 2.6 3.8 3.3 3.7 2.9 4.0 3.1 2.8
  I99. All Other Congenital Anomalies of
the Musculoskeletal System 		149.5 134.8 149.0 160.5 146.5 151.1 136.3 161.5 173.3 166.9 116.0

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2008,
Cases Diagnosed within One Year from Birth
(Continued)

Congenital Anomalies (740 - 759)
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
J Congenital Anomalies
of the Integument 		45.0 21.9 21.8 22.7 22.2 64.2 33.2 46.7 95.4 36.5 111.6
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
K Chromosomal Anomalies 21.6 20.6 21.4 21.2 21.7 21.8 21.7 22.3 22.6 20.6 21.9
  K01 Trisomy 13 0.9 1.1 0.7 0.7 1.1 0.9 0.9 1.3 0.6 0.8 0.8
  K02 Down Syndrome 12.5 10.5 13.0 13.1 10.9 12.9 13.4 13.5 13.6 11.5 12.6
  K03 Trisomy 18 1.4 1.0 1.4 1.6 2.1 1.3 1.2 1.2 1.4 1.1 1.5
  K99. All Other Chromosomal Anomalies 8.0 9.4 7.4 7.5 9.1 7.7 7.0 7.9 7.4 8.4 7.7
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
L Other and Unspecified
Congenital Anomalies 		43.0 46.1 57.3 50.2 54.4 35.4 48.7 46.8 36.1 28.8 15.4
                      

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2008,
Cases Diagnosed within One Year from Birth
(Continued)

Other Reportable Conditions

Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
M Infectious Conditions
Occurring in the Perinatal
Period 		9.3 12.3 12.3 12.6 9.9 7.2 6.5 5.9 6.5 4.1 13.5
  M01 Syphilis 1.4 1.4 2.2 1.2 2.5 1.0 * 1.0 0.9 * 2.3
  M02 Other Infections 7.9 10.8 10.1 11.4 7.4 6.3 6.2 4.8 5.6 3.7 11.1
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
N Familial/Congenital
Neoplasms 		1.1 1.4 1.2 1.2 1.1 1.0 0.8 1.3 1.2 1.0 0.9
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
O Endocrine/Metabolic
Disorders 		35.7 35.7 35.0 36.2 32.8 36.3 30.0 36.6 40.9 34.9 39.5
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
P Diseases of the Blood
& Blood Forming Organs 		19.7 17.7 16.2 19.4 20.1 20.9 18.2 23.8 22.0 19.9 20.6
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
Q Other Diseases of the
Central and Peripheral
Nervous System 		24.1 26.5 26.7 27.3 24.3 22.4 24.6 26.5 24.9 20.3 15.2
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
R Other Diseases of the Eye 51.7 52.1 52.0 53.6 52.0 51.2 52.1 56.6 52.4 51.1 43.3
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
S Hearing Deficiency 33.3 28.5 36.4 37.3 33.4 32.8 29.7 36.9 34.7 30.4 32.4
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
T Other Diseases of the
Heart & Circulatory System 		33.4 38.2 32.6 34.3 32.4 32.6 26.8 31.1 36.7 33.0 35.4

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2008,
Cases Diagnosed within One Year from Birth
(Continued)

Other Reportable Conditions
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
U Other Diseases of the
Gastrointestinal System 		61.5 64.9 69.1 64.1 61.0 58.8 59.0 63.9 58.9 56.9 55.2
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
V Other Diseases of the
Genital and Urinary Systems 		3.3 4.0 3.5 3.6 3.9 2.9 3.9 3.1 3.5 2.2 1.5
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
W Other Fetal/Placental
Anomalies 		1.0 - - * * 1.8 * 8.6 * - -
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
X Other Musculoskeletal
System Diseases 		0.2 * * * 0.5 0.1 * * * * *
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
Y Maternal Exposures
Affecting Fetus 		20.0 26.1 26.4 19.9 14.9 18.4 17.5 19.6 19.7 11.7 23.5
  Y01 Fetal Alcohol Syndrome 1.3 1.9 1.7 1.4 1.0 1.2 1.2 1.3 1.6 0.8 0.8
  Y99. Other Maternal Exposures
Affecting the Fetus 		19.0 24.6 25.4 18.8 14.1 17.4 16.4 18.5 18.4 11.2 22.9
Diagnostic Grouping2000
to
2008		20002001200220032004
to
2008		20042005200620072008
One or More
Reportable Diagnosis 		 761.9 714.4 749.4 745.3 722.1 786.4 725.5 818.7 873.2 755.5 758.2
                      

Notes:
Rates are per 10,000 Michigan Born Resident Live Births. Rates include all children reported with a birth defect who were born in Michigan and whose mother was a resident at the time of birth. This enables the calculation of birth defects prevalence rates. Birth defect statistics sometimes reflect trends related to data reporting or new testing. See Data Quality Considerations for further details.
*: A rate is not calculated when there are fewer than 6 events, because the width of the confidence interval would negate any usefulness for comparative purposes.
Conditions are reportable if identified within the first two years of a child's life. The prevalence frequencies used to calculate the rates in this table represent cases diagnosed within the first year of life.
Diagnoses are coded using the 9th revision to the International Classification of Diseases - ICD 9 CM.  Diagnostic Code Groupings used for congenital anomaly codes are as used by the Centers for Disease Control. (See Birth Defect Groups and ICD-9-CM Diagnosis Codes for the codes used to categorize birth defects.)
Source: Michigan Birth Defects Registry, Division for Vital Records & Health Statistics, Michigan Department of Community Health
Reports Processed through October 29, 2010

Last Updated on January 26, 2011


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