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Interpretation of HIV Test Results 1. HIV antibody testing should be
performed according to current recommendations, which includes the use of an enzyme
immunoassay (EIA) to test for antibody to HIV and confirmatory testing with an additional,
more specific assay (e.g., Western blot or immunofluorescence assay [IFA]). All assays
should be performed and conducted according to manufacturers' instructions and applicable
state and federal laboratory guidelines.
4. HIV infection (as indicated by the
presence of antibody to HIV) is defined by Michigan law as a repeatedly reactive EIA and a
positive confirmatory supplemental test. Women with persistent indeterminate test results
should be referred for further definitive antigen based testing (e.g., PCR ). Pregnant
women who have repeatedly reactive EIA and indeterminate supplemental tests should be
retested immediately for HIV antibody to distinguish between recent seroconversion and a
negative test result. Women with a positive test should always be retested to confirm the
positive status. Uncertainties regarding HIV infection status should be resolved before
final decisions are made concerning pregnancy termination, ZDV therapy, or other
interventions. |