Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2013,
Cases Diagnosed within One Year from Birth

Congenital Anomalies (740 - 759)

Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
A Congenital Anomalies of the
Central Nervous System
39.6 36.5 39.4 41.1 38.8 42.9 39.6 43.0 44.7 40.0 40.2 37.6 37.5 37.8 38.7 35.8
  A01 Anencephalus 1.0 1.4 0.5 1.2 1.2 1.5 1.0 0.7 0.9 0.5 1.3 1.2 0.8 1.0 1.0 1.4
  A02 Spina Bifida w/o Anencephaly 4.2 3.4 5.2 3.5 3.8 4.7 4.3 5.0 5.4 4.7 5.4 3.4 4.4 4.2 3.9 2.0
  A03 Hydrocephalus w/o Spina Bifida 9.3 10.2 11.7 10.4 9.4 10.5 8.6 10.1 9.7 10.5 10.1 8.8 8.0 6.9 7.0 6.1
  A04 Encephalocele 1.0 1.2 0.9 1.0 1.1 1.1 1.0 1.7 1.0 1.1 0.9 0.9 * 0.8 1.3 0.8
  A05 Microcephalus 9.7 9.2 9.0 10.9 9.2 9.8 9.8 10.4 11.6 10.6 7.1 8.2 10.1 10.0 8.8 10.8
  A99 All Other CNS
Anomalies
21.6 16.9 19.6 21.4 22.1 23.4 22.2 24.0 24.2 20.9 23.6 21.5 20.1 22.2 24.3 18.7
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
B Congenital Anomalies of the Eye 26.3 28.1 28.4 30.2 29.4 28.5 24.7 29.0 24.4 25.1 25.4 23.5 22.5 26.2 21.4 24.6
  B01 Anopthalmos/Micropthalmos 1.7 1.6 2.2 2.7 2.2 1.8 1.4 2.0 1.7 1.8 1.4 1.0 1.2 1.7 0.8 0.9
  B02 Congenital Cataract 2.3 2.9 2.5 3.0 2.9 2.4 2.0 3.0 1.6 2.2 2.5 1.2 2.4 2.7 1.4 1.0
  B03 Aniridia 0.3 * * * * 0.5 0.3 * * * * - * * * *
  B99 All Other Congenital
Anomalies of the Eye
24.1 25.8 26.1 26.9 26.5 26.0 22.7 26.2 22.9 22.4 23.0 22.2 20.1 23.4 20.4 23.5
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
C Congenital Anomalies of the
Ear, Face & Neck
16.2 16.3 17.8 19.0 16.7 15.6 15.7 20.1 15.2 14.0 16.9 13.2 15.3 15.4 14.5 16.0
  C01 Anotia/Microtia 1.3 1.6 1.6 1.6 1.9 1.5 1.2 1.1 1.1 1.1 1.3 1.0 1.6 1.5 1.1 0.5
  C99 All Other Congenital
Anomalies of the Ear,
Face & Neck
15.8 15.9 17.6 18.3 16.5 15.0 15.2 19.9 15.1 13.4 16.2 12.8 14.6 15.0 13.7 15.9
   

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2013,
Cases Diagnosed within One Year from Birth
(Continued)

Congenital Anomalies (740 - 759)

Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
D Congenital Anomalies of the
Heart & Circulatory System
185.8 157.9 173.2 186.3 184.1 200.4 189.2 207.5 216.4 194.4 199.5 173.8 170.3 178.2 189.7 167.1
  D01 Common Truncus 1.3 0.8 1.6 0.9 1.9 1.2 1.4 1.3 1.4 1.2 1.8 0.5 2.0 1.5 1.4 1.1
  D02 Transposition of Great
Vessels
5.2 5.0 4.5 5.1 4.4 4.8 5.4 6.7 5.8 5.4 5.1 5.6 6.0 4.7 5.4 4.3
  D03 Tetralogy of Fallot 5.5 5.6 5.2 5.5 6.3 4.4 5.5 5.5 5.9 5.0 6.7 4.3 6.2 6.4 5.5 4.1
  D04 Ventricular Septal Defect 41.7 40.2 40.4 43.6 41.8 43.0 41.7 46.9 45.3 42.8 46.0 35.6 38.3 39.8 45.7 33.4
  D05 Atrial Septal Defect 86.8 60.6 65.5 75.9 76.5 87.3 95.3 98.2 102.3 87.2 97.6 86.5 83.2 101.9 111.8 88.2
  D06 Endocardial Cushion Defect 5.5 4.8 5.6 5.9 6.7 6.0 5.4 5.6 6.4 5.2 5.6 4.6 5.2 5.8 6.0 3.8
  D07 Pulmonary Valve
Atresia & Stenosis
11.1 10.7 12.4 10.5 13.4 10.1 10.9 14.1 13.2 12.0 11.5 8.0 10.7 10.0 11.2 6.4
  D08 Tricuspid Valve
Atresia & Stenosis
1.5 1.3 2.2 2.0 1.7 0.8 1.4 1.8 0.9 1.5 1.9 1.0 1.6 1.4 1.4 0.9
  D09 Ebstein's Anomaly 1.4 2.6 3.6 2.9 1.4 0.8 0.8 1.0 0.9 0.6 1.0 0.6 0.8 0.8 1.2 0.6
  D10 Aortic Valve Stenosis 2.4 3.2 2.1 2.4 2.8 2.9 2.2 2.7 2.5 2.5 2.4 1.8 1.8 2.4 2.4 1.7
  D11 Hypoplastic Left Heart
Syndrome
4.3 3.4 5.2 4.4 4.2 4.1 4.3 5.0 3.8 4.4 4.1 4.9 3.2 3.8 5.3 4.2
  D12 Patent Ductus Arteriosis 55.3 41.5 49.5 52.0 58.5 58.8 57.3 65.3 69.3 58.5 63.7 51.6 52.1 60.7 57.1 35.0
  D13 Coarctation of Aorta 6.3 6.1 5.1 6.7 6.5 6.1 6.4 6.3 7.4 7.1 7.4 4.4 5.7 6.2 7.7 5.3
  D14 Pulmonary Artery Anomalies 17.9 18.7 22.4 23.3 21.5 19.2 15.9 23.8 24.2 20.4 21.0 19.6 17.3 10.5 1.8 1.6
  D99 All Other Congenital
Anomalies of the
Heart and Circulatory System
75.2 66.2 69.7 80.1 80.2 93.6 73.5 82.0 94.2 81.9 79.4 67.5 66.8 61.6 66.3 57.5
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
E Congenital Anomalies of the
Respiratory System
50.4 40.0 46.5 48.0 58.7 53.1 51.2 59.0 82.6 70.6 40.5 33.9 40.9 41.5 47.5 38.5
  E01 Lung Agenesis/Hypoplasia 7.0 6.4 5.8 6.6 11.9 9.0 6.4 7.6 6.0 5.2 6.3 7.4 9.7 6.5 5.5 3.8
  E02 Choanal Atresia 1.7 1.5 2.1 2.3 1.4 1.6 1.7 1.9 1.4 1.3 1.4 1.7 2.0 1.7 1.9 2.2
  E99 All Other Congenital
Anomalies of the Respiratory
System
43.9 33.7 40.5 42.2 48.2 44.9 45.2 52.7 77.7 65.7 34.9 26.4 31.7 35.4 42.4 34.2
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
F Cleft Palate & Cleft Lip 15.6 14.8 17.3 15.9 17.0 15.2 15.4 16.1 18.0 15.9 15.3 17.4 13.9 14.9 14.0 12.5
  F01 Cleft Palate 5.4 5.2 6.4 5.5 5.5 5.2 5.4 6.1 6.7 6.1 5.7 6.6 3.6 4.0 4.3 4.8
  F02 Cleft Lip w & w/o Cleft Palate 10.2 9.6 10.8 10.5 11.5 10.0 10.0 10.0 11.3 9.8 9.6 10.8 10.3 10.9 9.7 7.7
   

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2013,
Cases Diagnosed within One Year from Birth
(Continued)

Congenital Anomalies (740 - 759)

Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
G Congenital Anomalies
of the Upper Alimentary Canal/
Digestive System
54.4 57.4 62.6 60.4 50.7 53.8 52.8 53.9 63.2 55.9 57.6 53.2 46.3 48.3 50.0 44.9
  G01 Esophageal Atresia/
Tracheoesophageal Fistula
2.8 2.5 3.5 3.5 3.6 3.6 2.5 3.4 2.8 3.2 2.4 1.2 2.5 2.4 2.1 1.8
  G02 Rectal and Large Intestinal
Atresia/Stenosis
4.8 5.5 4.7 5.1 4.6 5.0 4.8 4.8 5.9 4.5 4.5 4.0 5.0 5.3 4.1 4.6
  G03 Pyloric Stenosis 17.2 18.8 23.3 20.3 16.0 15.8 16.2 15.4 18.5 16.8 20.0 18.8 13.8 13.9 15.7 12.1
  G04 Hirshsprung's Disease
(congenital megacolon)
3.2 3.3 3.8 3.3 3.2 3.3 3.0 2.9 3.0 2.8 2.9 2.1 4.3 3.7 2.9 2.8
  G05 Biliary Atresia 1.2 1.2 1.1 0.8 1.2 1.4 1.2 1.0 1.0 0.9 1.3 1.2 1.1 1.6 1.4 1.1
  G99 Other Cong. Anomalies
of Upper Alimentary Canal
/ Digestive System
28.9 30.1 29.6 31.4 26.2 28.8 28.7 30.3 35.2 30.9 30.2 28.8 23.2 26.0 27.4 25.0
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
H Congenital Anomalies of the
Genital and Urinary Systems
138.6 151.4 142.6 145.8 141.9 144.7 134.5 157.2 158.2 145.3 126.1 104.0 102.9 138.0 140.0 133.3
  H01 Renal Agenesis/Hypoplasia 5.6 7.3 5.6 6.6 5.9 5.0 5.4 5.5 4.8 6.2 6.9 4.3 4.5 4.6 5.4 6.2
  H02 Bladder Exstrophy 0.3 * 0.8 0.5 * * 0.2 0.5 * * * * * * - *
  H03 Obstructive Genitourinary
Defects
22.7 19.5 21.8 23.0 23.2 23.4 23.0 25.7 24.4 23.7 23.1 17.4 17.8 24.1 27.3 22.7
  H04 Hypospadias &
Epispadias
31.8 33.6 29.9 31.5 30.1 29.2 32.4 37.6 26.7 29.6 36.4 29.9 30.6 39.5 31.8 29.8
  H99 All Other Congenital
Anomalies of the Genital
& Urinary Systems
113.2 124.3 118.2 120.4 119.2 123.5 108.2 129.3 138.2 123.6 95.5 78.6 76.9 104.6 115.0 106.1
   

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2013,
Cases Diagnosed within One Year from Birth
(Continued)

Congenital Anomalies (740 - 759)

Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
I Congenital Anomalies of the
Musculoskeletal System
169.9 155.5 171.5 178.5 164.7 154.0 173.0 179.2 194.5 186.4 140.2 120.3 154.4 170.3 207.6 202.9
  I01 Upper Limb
Reduction Deformities
2.5 3.0 2.7 2.7 2.6 2.1 2.4 2.1 2.1 2.9 3.0 2.3 2.7 2.8 2.0 2.0
  I02 Lower Limb
Reduction Deformities
1.9 1.7 2.2 2.0 1.9 1.9 1.8 2.3 2.3 1.7 1.5 2.0 1.6 1.5 2.1 1.2
  I03 Gastroschisis/Omphalocele 6.2 3.8 5.2 3.4 5.3 5.9 7.1 6.1 7.4 6.7 6.1 6.1 8.7 7.2 7.8 8.5
  I03a Omphalocele --- --- --- --- --- --- --- --- --- --- --- --- 1.9 1.7 2.4 1.4
  I03b Gastroschisis --- --- --- --- --- --- --- --- --- --- --- --- 5.3 4.9 3.8 3.4
  I03c Other & Unspecified
Abdominal Wall Anomalies
4.7 3.8 5.1 3.4 5.2 5.9 4.7 6.1 7.4 6.7 5.9 5.0 2.9 1.6 2.3 4.0
  I04 Congenital Hip Dislocation 11.9 14.8 16.3 16.1 13.0 11.5 10.4 9.4 13.0 8.1 12.2 12.0 10.4 11.9 9.6 6.6
  I05 Diaphragmatic Hernia 3.3 2.9 3.3 2.7 3.8 3.7 3.3 2.9 4.1 3.4 3.2 3.9 3.6 3.3 2.4 2.3
  I99 All Other
Congenital Anomalies of
the Musculoskeletal System
153.2 136.7 151.7 162.8 148.1 138.2 156.9 164.5 176.6 172.3 124.4 103.6 136.0 152.9 191.4 188.4
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
J Congenital Anomalies
of the Integument
63.0 22.4 22.9 23.7 23.1 34.7 86.2 48.8 100.1 38.7 113.1 103.3 75.5 93.9 71.3 136.5
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
K Chromosomal Anomalies 22.3 20.8 22.0 21.7 21.9 22.5 22.6 23.0 23.7 21.2 23.6 23.2 23.6 23.3 23.7 18.3
  K01 Trisomy 13 0.6 0.8 0.5 0.5 0.9 0.7 0.6 1.0 * * * 0.5 * 0.8 0.9 0.6
  K02 Down Syndrome 12.7 10.8 13.1 13.5 11.0 13.6 12.8 13.8 14.6 11.7 12.7 11.6 14.8 12.6 13.1 10.3
  K03 Trisomy 18 1.4 1.0 1.6 1.6 2.2 1.2 1.4 1.3 1.5 1.2 1.9 1.5 0.9 1.4 1.3 1.3
  K99 All Other
Chromosomal Anomalies
8.7 9.4 7.9 7.7 9.1 7.6 9.0 8.5 7.7 8.9 8.9 10.5 8.5 10.4 10.2 7.5
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
L Other and Unspecified
Congenital Anomalies
75.4 46.5 57.2 50.3 54.6 49.7 90.1 47.6 36.9 30.0 19.1 15.5 165.9 160.3 177.7 181.5
   

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2013,
Cases Diagnosed within One Year from Birth
(Continued)

Other Reportable Conditions

Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
M Infectious Conditions
Occurring in the Perinatal
Period
29.0 46.5 57.2 50.3 54.6 49.7 15.0 13.1 15.9 11.0 20.7 15.8 17.6 19.0 13.0 9.3
  M01 Syphilis 1.2 1.6 2.2 1.2 2.3 * 0.9 1.1 1.0 * 1.3 1.6 * * 0.7 1.3
  M02 Other Infections 14.3 12.6 13.7 17.0 14.4 14.9 14.1 12.0 14.9 10.7 19.4 14.1 17.3 18.6 12.2 8.0
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
N Familial/Congenital
Neoplasms
1.1 1.1 1.1 1.0 1.2 0.9 1.1 1.5 1.5 1.3 1.3 * 0.7 1.2 1.0 0.9
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
O Endocrine/Metabolic
Disorders
39.2 37.1 34.7 36.6 33.1 31.0 42.0 38.7 41.4 34.3 42.6 34.4 43.3 43.4 55.5 46.1
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
P Diseases of the Blood
& Blood Forming Organs
23.1 18.2 16.8 20.2 20.1 18.9 25.8 24.6 23.2 20.2 24.0 20.3 27.4 30.9 32.0 30.7
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
Q Other Diseases of the
Central and Peripheral
Nervous System
25.7 28.1 27.2 28.3 25.7 27.4 24.6 28.8 29.3 25.0 25.9 21.9 20.8 27.9 22.3 18.6
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
R Other Diseases of the Eye 49.3 54.4 53.2 55.5 52.8 53.6 46.5 59.4 56.3 56.5 52.0 41.1 37.0 43.9 37.9 30.3
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
S Hearing Deficiency 46.5 29.7 43.8 47.8 36.2 32.4 51.8 40.8 37.8 32.6 37.3 33.9 46.2 78.5 80.5 84.5
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
T Other Diseases of the
Heart & Circulatory System
35.2 39.2 33.6 36.1 33.1 27.7 36.0 32.2 38.8 35.5 37.9 33.9 35.2 34.7 45.4 30.6
   

Table 11
Birth Defect Prevalence Rates by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2000-2013,
Cases Diagnosed within One Year from Birth
(Continued)

Other Reportable Conditions

Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
U Other Diseases of the
Gastrointestinal System
61.0 66.7 71.8 65.6 62.6 61.1 58.2 67.2 62.8 61.1 60.3 44.0 51.7 54.4 62.5 58.0
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
V Other Diseases of the
Genital and Urinary Systems
2.1 1.6 1.7 2.2 2.5 3.0 2.0 2.5 2.6 1.1 1.3 2.3 2.0 2.2 2.2 1.3
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
W Other Fetal/Placental
Anomalies
0.7 - - * * * 1.1 8.5 * * - - * * - -
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
X Other Musculoskeletal
System Diseases
0.2 * * * 0.5 * 0.2 * * * * * * * * *
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
Y Maternal Exposures
Affecting Fetus
19.0 12.3 12.1 11.8 8.5 11.1 23.8 14.3 13.3 12.7 18.5 17.0 22.5 35.1 41.0 44.0
  Y01 Fetal Alcohol Syndrome 1.1 1.9 1.7 1.7 1.0 1.3 0.9 1.3 1.6 0.9 * * 0.9 0.6 0.7 1.1
  Y99 Other Maternal Exposures
Affecting the Fetus
17.9 10.4 10.4 10.2 7.5 9.9 23.0 13.1 11.7 11.9 18.2 16.6 21.7 34.7 40.4 43.0
   
Diagnostic Grouping2000
to
2013
200020012002200320042005
to
2013
200520062007200820092010201120122013
One or More
Reportable Diagnosis 
840.7 751.1 796.9 798.1 752.5 763.6 882.8 872.0 921.8 797.5 805.9 693.0 852.6 950.1 1,013.2 1,053.4
   

Notes:
Rates are per 10,000 Michigan Born Resident Live Births. Rates include all children reported with a birth defect who were born in Michigan and whose mother was a resident at the time of birth. This enables the calculation of birth defects prevalence rates. Birth defect statistics sometimes reflect trends related to data reporting or new testing. See Data Quality Considerations for further details.
*: A rate is not calculated when there are fewer than 6 events, because the width of the confidence interval would negate any usefulness for comparative purposes.
Conditions are reportable if identified within the first two years of a child's life. The prevalence frequencies used to calculate the rates in this table represent cases diagnosed within the first year of life.
Diagnoses are coded using the 9th revision to the International Classification of Diseases - ICD 9 CM.  Diagnostic Code Groupings used for congenital anomaly codes are as used by the Centers for Disease Control. (See Birth Defect Groups and ICD-9-CM Diagnosis Codes for the codes used to categorize birth defects.)
Source: Michigan Birth Defects Registry, Division for Vital Records & Health Statistics, Michigan Department of Health & Human Services
Reports Processed through January 10, 2016

Last Updated on August 1, 2016